TY - JOUR AU - Özçimen, Emel Ebru AU - Üçkuyu, Ayla AU - Üstüner, Işık AU - Yanık, Filiz Fatma AU - Kulaksızoğlu, Sevsen AU - Öktem, Mesut AU - Eroğlu, Derya AU - Kuşçu, Esra PY - 2006/12/20 Y2 - 2024/03/28 TI - Helicobacter Pylori Positivity in Patients with Hyperemesis Gravidarum JF - Gynecology Obstetrics & Reproductive Medicine JA - Gynecol Obstet Reprod Med VL - 12 IS - 3 SE - Obstetrics; Maternal Fetal Medicine and Perinatology DO - UR - https://www.gorm.com.tr/index.php/GORM/article/view/595 SP - 165-168 AB - <p>OBJECTIVE: To investigate the relationship between Helicobacter pylori (H. py lori) infection and hyperemesis gravidarum (HG) by using H. pylori specific serum antibody test and H. pylori stool antigen (HpSA).<br />MATERIAL AND METHODS: This prospective cross-sectional study was carried out on 70 pregnant women with HG and 70 healthy pregnant women. Serum immunoglobulin G antibody for H. pylori and HpSA were assayed in both groups. Chi-square test was used f or statistical analysis.<br />RESULTS: The study and control groups were matched regarding the maternal age, gestational weeks, gravida and parity. Positive serum IgG concentrations were found in 35 of the 70 HG patients (50%) compared with 33 of 70 controls (47.1%), (p&gt;0.05). The rate of HpSA positivity was 32.8% (23/70) and 21.4% (15/70) respectiv ely (p&gt;0.05).<br />CONCLUSION: Contradicting with most of the studies which investigated the relationship between H. pylori infection and HG, our results indicate no significant relationship between HG and H. pylori IgG and HpSA.</p> ER -