Perinatal Outcome of Fetal Echogenic Bowel: A Single-Center Retrospective Cohort Study

Authors

DOI:

https://doi.org/10.21613/GORM.2019.864

Keywords:

Echogenic bowel, Aneuploidy, Perinatal outcome

Abstract

Objective: The aim of this study is to evaluate perinatal outcome of fetal echogenic bowel.

Study Design: In this retrospective cohort study, fetuses with echogenic bowel diagnosed and followed in our center between 2013-2017 were included. Fetuses and infants were evaluated in terms of antenatal comorbidities and postnatal persistent diseases. Infants were followed-up to June 2018 from time of diagnosis. Demographic questionnaire and face to face interview were used to obtain data including immune system diseases and respiratory system pathologies in infants.

Results: A total of 100 fetuses with echogenic bowel were included in the study. Fetal aneuploidy was detected in 7 (7%) cases. Trisomy 21 was the most common aneuploidy and identified in 4 (4%) cases. Other chromosomal disorders were tetrasomy 12p (1%), 69XXX (1%) and 46 XX, t (2,22) (9q9) (1%). A fetal echogenic bowel was associated with major congenital malformations in 25 (%25) cases. Cardiac abnormality was the most prevalent (%7). First and second trimester vaginal bleeding history was found in 5 pregnant women. In 3 case with isolated echogenic bowel (no congenital malformation and aneuploidy), lactose intolerance, celiac disease, and non-obstructive hydrocephalus were diagnosed in early childhood.

Conclusion: Isolated fetal echogenic bowel which can be considered as a soft marker for aneuploidy may be associated with lactose intolerance and celiac disease. Further clinical studies are warranted to evaluate this relationship.

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Author Biographies

Hidayet Sal, Karadeniz technical university

Deparment of Obstetrics and Gynecology

Erhan Huseyin Comert, Karadeniz Technical University

Department of Obstetric and Gynecology

Yasin Semih Ekici, Karadeniz Technical University

Department of Obstetric and Gynecology

Turhan Aran, Karadeniz Technical University

Department of Obstetric and Gynecology

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Published

2021-04-16

How to Cite

1.
Sal H, Comert EH, Ekici YS, Aran T. Perinatal Outcome of Fetal Echogenic Bowel: A Single-Center Retrospective Cohort Study. Gynecol Obstet Reprod Med [Internet]. 2021Apr.16 [cited 2021Jul.28];27(1):1-5. Available from: https://www.gorm.com.tr/index.php/GORM/article/view/864

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Section

Obstetrics; Maternal Fetal Medicine and Perinatology

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