Role of Oocyte Morphological Abnormality Rates on the Embryo Development and Implantation

Authors

  • Bulent Emre Bilgic Zeynep Kamil Women and Children’s Health Training and Research Hospital
  • Cigdem Yayla Abide Zeynep Kamil Women and Children’s Health Training and Research Hospital
  • Enis Ozkaya Zeynep Kamil Women and Children’s Health Training and Research Hospital
  • Tayfun Kutlu Zeynep Kamil Women and Children’s Health Training and Research Hospital
  • Sule Ayla Zeynep Kamil Women and Children’s Health Training and Research Hospital
  • Ilhan Sanverdi Regenerative and restorative medical center, Istanbul Medipol University
  • Gulden Tunali Zeynep Kamil Women and Children’s Health Training and Research Hospital
  • Erdal Yucel Zeynep Kamil Women and Children’s Health Training and Research Hospital
  • Savas Kanbur Gedik University

DOI:

https://doi.org/10.21613/GORM.2018.755

Keywords:

Oocyte morphology, embryo implantation, fertilization, ICSI

Abstract

OBJECTIVE: The aim of this study was to assess the impact of some oocyte morphological abnormality rates on embryo development and implantation.

STUDY DESIGN: Oocyte morphological abnormalities including oocyte size, elliptical shape, vacuole, plain polar body, fragmented polar body, large perivitellin space, perivitellin debris, central granulation, dense central granulation, inclusion body, thick zona pellucida, clusters of smooth endoplasmic reticulum, easy needle insertion and dark cytoplasm were determined for each oocyte. Rates of these oocyte morphological anomalies were determined for each case and the impact of rates on the cycle outcome was analyzed.

RESULTS: Similar oocyte morphology abnormality rates were observed between cycles with and without successful embryo implantation. On the other hand, both fragmented polar body and vacuole rates were found to be significantly higher in cycles with Grade 2 embryo transfer. These rate differences were remained significant after adjustment for the age and basal FSH level.

CONCLUSION: None of the oocyte morphological features was found to have significant impact on ART outcome. 

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Author Biographies

Bulent Emre Bilgic, Zeynep Kamil Women and Children’s Health Training and Research Hospital

Department of Obstetrics and Gynecology

MD

Cigdem Yayla Abide, Zeynep Kamil Women and Children’s Health Training and Research Hospital

Department of Obstetrics and Gynecology

MD

Enis Ozkaya, Zeynep Kamil Women and Children’s Health Training and Research Hospital

Department of Obstetrics and Gynecology

MD

Tayfun Kutlu, Zeynep Kamil Women and Children’s Health Training and Research Hospital

Department of Obstetrics and Gynecology

MD

Sule Ayla, Zeynep Kamil Women and Children’s Health Training and Research Hospital

Department of Obstetrics and Gynecology

MD

Ilhan Sanverdi, Regenerative and restorative medical center, Istanbul Medipol University

Department of Histology and EmbryologY

MD

Gulden Tunali, Zeynep Kamil Women and Children’s Health Training and Research Hospital

Department of Histology and Embryolog

MD

Erdal Yucel, Zeynep Kamil Women and Children’s Health Training and Research Hospital

Department of Obstetrics and Gynecology

Savas Kanbur, Gedik University

Department of Obstetrics and Gynecology

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Published

2018-12-25

How to Cite

1.
Bilgic BE, Yayla Abide C, Ozkaya E, Kutlu T, Ayla S, Sanverdi I, Tunali G, Yucel E, Kanbur S. Role of Oocyte Morphological Abnormality Rates on the Embryo Development and Implantation. Gynecol Obstet Reprod Med [Internet]. 2018Dec.25 [cited 2021Apr.15];24(3):131-8. Available from: https://www.gorm.com.tr/index.php/GORM/article/view/755

Issue

Section

Reproductive Medicine: Endocrinology and Infertility

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