Comparison of the Different Type and the Different Routes of Administration of Human Chorionic Gonadotropin During Trigger of Ovulation in ICSI Cycles and the Relation with Body Mass Index
Keywords:Body mass index, Oosyte maturation, Human chorionic gonadotropin
OBJECTIVE: To confirm that HcG levels in follicular fluid and serum after intramuscular (IM) or subcutaneous(SC) administration of purified (p)HcG and SC administration of recombinant(r)HcG and their associations with body mass index (BMI) and oocytes maturation in ICSI cyle.
STUDY DESIGN: We used pHcG or rHcG for triggering ovulation of all patients . Group1(n:56) received IMpHcG and Group2(n:57) received SCpHcG and Group3( n:47) received rHcG . Serum and follicular fluid HcG levels were measured on the day of oocytes retrieved as primary outcome.
RESULT: There was a significant difference on serum and follicular fluid HcG levels among three groups. No correlation was found between BMI and oocytes maturation for Group1 and Group2. But there was a significantly negative correlation between BMI and oocytes maturation in Group3.
CONCLUSION: When comparing the different administration routes of HcG , the S.C. route of HcG seems to be safer and useful for obese patients.
How to Cite
All the articles published in GORM are licensed with "Creative Commons Attribution 4.0 License (CC BY 4.0)". This license entitles all parties to copy, share and redistribute all the articles, data sets, figures and supplementary files published in this journal in data mining, search engines, web sites, blogs and other digital platforms under the condition of providing references.