Serum Ischemia Modified Albumin Levels in Infertile Couples Underwent in Vitro Fertilization

Authors

  • Fatma Beyazıt Department of Reproductive Endocrinology and IVF Department Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara
  • Osman Balcı Department of Obstetrics and Gynecology Meram Medicine Faculty Selcuk University, Konya
  • Magdi Adam Department of Reproductive Endocrinology and IVF Department Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara
  • Hasan İnal Department of Reproductive Endocrinology and IVF Department Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara
  • Yeşim Bardakcı Department of Reproductive Endocrinology and IVF, Laboratory of ART and Embryology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara
  • Nafiye Yılmaz Department of Reproductive Endocrinology and IVF Department Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara

Keywords:

In vitro fertilization, Infertility, Ischemia modified albumin

Abstract

OBJECTIVE: Ischemia-modified albumin (IMA) is a novel biomarker for diagnosis of distinct disease states including infectious diseases, coronary atherosclerotic disease, hypoxic fetal distress and diabetes mellitus. In vitro fertilization (IVF) is a medical process by which an egg is fertilized by sperm outside the body with varible success rates. It is important for the clinician to assess which women will get pregnant after IVF procedure. In this context we aimed to analyse the possible role of IMA in infertile couples underwent IVF.

STUDY DESINGN: The study group comprised 30 patients with IVF failure, 27 patients with a successful IVF cycle and 34 fertile controls. IVF failure is defined as IVF that does not result in a pregnancy. A rapid, spectrophotometric Albumin Cobalt Binding (ACB) test was used to determine serum IMA levels and results were presented by absorbance units (ABSU).

RESULTS: Serum IMA levels were 0.27 (0.07-0.58), 0.35(0.08-0.88), and 0.37(0.06-1.07) ABSU for patients with IVF cycle failure, successful IVF cycle and controls respectively. No statistically significant difference was observed between study participants.

CONCLUSION: Our results showed that ischemia modified albumin did not provide enough sensitivity or specificity to determine IVF success.

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Published

2015-04-30

How to Cite

1.
Beyazıt F, Balcı O, Adam M, İnal H, Bardakcı Y, Yılmaz N. Serum Ischemia Modified Albumin Levels in Infertile Couples Underwent in Vitro Fertilization. Gynecol Obstet Reprod Med [Internet]. 2015Apr.30 [cited 2021Mar.7];21(1):14-7. Available from: https://www.gorm.com.tr/index.php/GORM/article/view/38

Issue

Section

Reproductive Medicine: Endocrinology and Infertility

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