An Obstetrics Index for the Assessment of Risk Levels of “High Risk Pregnancy” Groups

Authors

  • M. Sinan Beksaç Hacettepe University Medical Faculty Division of Perinatal Medicine, Ankara
  • Emine Aydın Hacettepe University Medical Faculty Division of Perinatal Medicine, Ankara
  • Mert Tuğral Hacettepe University Medical Faculty Division of Perinatal Medicine, Ankara
  • Ergün Karaağaoğlu Hacettepe University Medical Faculty Department of Bioistatistics, Ankara

Keywords:

Perinatal morbidity & mortality, High risk pregnancy, Beksac obstetrics index

Abstract

OBJECTIVE: To validate the usability of “Beksaç Obstetrics Index” (BOI/BOIp) in the evaluation of different high risk pregnancy groups.

STUDY DESIGN: This study is consisted of 3 groups of patients; 1) Pregnancies without MTHFR polymorphisms (n=65), 2) Pregnancies with methylenetetrahydrofolate reductase (MTHFR; homozygous or compound heterozygous) polymorphisms (n=140), 3) Pregnancies with “autoimmune antibody positivity” without any other type of hereditary thrombophilia (Anti-dsDNA, anti-phospholipid Ig G/M, anti-cardiolipin Ig G/M, ASMA, APA, ENA, anti-mitochondrial antibodies) (n=76). In this study, BOI which is (number of child +π/10)/Gravida is used in order to demonstrate the risk levels/scale of different high risk pregnancy groups.

RESULTS: The mean BOIp (±SD) values are 0,41±0,22; 0,29±0,21; and 0,40±0,23 for Control, MTHFR and Autoimmune groups respectively. We have demonstrated statistically significantly decreased BOIp level in MTHFR group compared to the other groups (p:0,002).

CONCLUSION: We have demonstrated that BOI/BOIp can be used in the assessment of risk levels of different high risk pregnancy groups.

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Published

2015-04-30

How to Cite

1.
Beksaç MS, Aydın E, Tuğral M, Karaağaoğlu E. An Obstetrics Index for the Assessment of Risk Levels of “High Risk Pregnancy” Groups. Gynecol Obstet Reprod Med [Internet]. 2015Apr.30 [cited 2022Aug.9];21(1):10-3. Available from: https://www.gorm.com.tr/index.php/GORM/article/view/37

Issue

Section

Obstetrics; Maternal Fetal Medicine and Perinatology

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