Is Weekly Supplementation of Vitamin D Favorable for Treatment of Osteoporosis in Postmenopausal Women?

Authors

  • Mehmet Şükrü Budak Cizre State Hospital, Şırnak
  • Sedat Akgöl Kızıltepe State Hospital, Mardin
  • Şahin Önen Kızıltepe State Hospital, Mardin
  • Selami Erdem Bismil State Hospital, Diyarbakır
  • Serkan Kahyaoğlu Dr. Zekai Tahir Burak Women Health Research and Education Hospital, Ankara
  • Mine Kanat Pektaş Kocatepe University Hospital, Afyonkarahisar

Keywords:

Calcium, Osteoporosis, Postmenopausal, Vitamin D

Abstract

OBJECTIVE: The present study aims to determine whether once weekly supplementation of vitamin D and alendronate is efficient and safe for treatment of postmenopausal osteoporosis.
STUDY DESIGN: Group I (42 women with postmenopausal osteoporosis) received daily supplementation of calcium (1000 mg) and vitamin D (880 IU) while group II (42 women with postmenopausal osteoporosis) had weekly supplementation of vitamin D (2800 IU) along with weekly treatment of alendronate (70 mg).
RESULTS: Group I had significantly lower lumbar spine T-scores before and after treatment. Post-treatment lumbar spine T-scores and femur neck T-scores were significantly higher with respect to pre-treatment scores in both study groups. The alterations in lumbar spine and femur neck T-scores were statistically similar in both group I and group II.
CONCLUSION: Once weekly administration of vitamin D and alendronate is an effective and safe option of treatment for women who cannot take calcium supplements for postmenopausal osteoporosis.

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Published

2012-08-06

How to Cite

1.
Budak M Şükrü, Akgöl S, Önen Şahin, Erdem S, Kahyaoğlu S, Kanat Pektaş M. Is Weekly Supplementation of Vitamin D Favorable for Treatment of Osteoporosis in Postmenopausal Women?. Gynecol Obstet Reprod Med [Internet]. 2012Aug.6 [cited 2024Mar.28];18(2):78-82. Available from: https://www.gorm.com.tr/index.php/GORM/article/view/245

Issue

Section

Gynecology and Gynecological Oncology