Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders

Authors

  • İnci Kahyaoğlu Etlik Zübeyde Hanım Women’s Health Teaching and Research Hospital, Department of IVF, Ankara
  • Nafiye Yılmaz Zekai Tahir Burak Women's Health Education and Research Hospital, Department of IVF, Ankara
  • Serkan Kahyaoğlu Zekai Tahir Burak Women's Health Education and Research Hospital, Department of IVF, Ankara
  • Ayten Türkkanı Etlik Zübeyde Hanım Women’s Health Teaching and Research Hospital, Department of IVF, Ankara
  • Mahmut Nedim Çiçek Zekai Tahir Burak Women's Health Education and Research Hospital, Department of IVF, Ankara
  • Leyla Mollamahmutoğlu Etlik Zübeyde Hanım Women’s Health Teaching and Research Hospital, Department of IVF, Ankara

Keywords:

Androgen, Normoresponder, In vitro fertilization

Abstract

OBJECTIVE: The purpose of the present study is to evaluate the predictive value of basal total testosterone (total-T) and dehydroepiandrosterone sulphate (DHEAS) levels in normoresponder patients undergoing IVF-ET.
STUDY DESIGN: A total of 60 normoresponder infertile women, scheduled to undergo their first IVF/ET cycle were enrolled in this study. Day 2-4 basal concentrations of FSH, LH, E2, total testosterone, DHEAS and antral follicle count (AFC) were determined in preceding cycle.
RESULTS: No significant difference was found between pregnant and non-pregnant groups regarding the AFC, hormone and controlled ovarian hyperstimulation (COH) parameters (total dose of gonadotrophins (1995.7±851.1 vs 2296.4±845.3 IU), >14 mm follicles (9.3±3.1 vs 7.3±3.9), retrieved oocytes (12.4±5.1 vs 8.7±6.1) or number of good quality embryos (7.4±3.7 vs 4,4±3.6) (p>0.05). Testosterone and DHEAS was not correlated with COH parameters (p>0.05).
CONCLUSION: There is no correlation between testosterone and DHEAS levels and COH parameters in normoresponder IVF patients.

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Published

2013-12-30

How to Cite

1.
Kahyaoğlu İnci, Yılmaz N, Kahyaoğlu S, Türkkanı A, Çiçek MN, Mollamahmutoğlu L. Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders. Gynecol Obstet Reprod Med [Internet]. 2013Dec.30 [cited 2021Sep.26];19(3):171-5. Available from: https://www.gorm.com.tr/index.php/GORM/article/view/212

Issue

Section

Reproductive Medicine: Endocrinology and Infertility

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