Comparison of the Effects of Copper T and Levonorgestrel IUD on Proteoglycan Composition of Cervical Mucus

Authors

  • Yeşim Bayoğlu Tekin Department of Gynecology and Obstetrics, Recep Tayyip Erdogan University, Rize
  • Emine Seda Güvendağ Güven Department of Gynecology and Obstetrics, Recep Tayyip Erdogan University, Rize
  • Zihni Açar Yazıcı Department of Microbiology, Recep Tayyip Erdogan University, Rize
  • Aynur Kırbaş Department of Biochemistry School, Recep Tayyip Erdogan University, Rize
  • Figen Kır Şahin Department of Gynecology and Obstetrics, Recep Tayyip Erdogan University, Rize

Keywords:

Cervical mucus, Copper T IUD, Levonorgestrel IUD

Abstract

OBJECTIVE: The aim of this study was to determine the effects of Copper T and Levonorgestrel IUD (LNG-IUD) on the proteoglycan composition of cervical mucus.
STUDY DESIGN: This was a cross-sectional study that was conducted at a gynecology outpatient clinic of a University hospital for a six month period. The study participants were between 18-50 years old, using either Copper T or LNG-IUD for contraception. Cervical mucus samples were collected 7 days after the menstrual bleeding and the levels of hyaluronan (HA), heparin sulfate (HS) and sulfated-glycosaminoglycans (s-GAG) were evaluated.
RESULTS: The levels of HA, HS and s-GAG in the Copper-T and LNG-IUD groups were higher than those of the controls. However, the difference was statistically significant only for s-GAG (p<0.001).
CONCLUSION: Copper T and Levonorgestrel intrauterine contraceptive devices have significant effects on proteoglycan component of cervical mucus.

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Published

2014-12-30

How to Cite

1.
Bayoğlu Tekin Y, Güvendağ Güven ES, Yazıcı ZA, Kırbaş A, Kır Şahin F. Comparison of the Effects of Copper T and Levonorgestrel IUD on Proteoglycan Composition of Cervical Mucus. Gynecol Obstet Reprod Med [Internet]. 2014Dec.30 [cited 2021May6];20(3):159-62. Available from: https://www.gorm.com.tr/index.php/GORM/article/view/164

Issue

Section

Reproductive Medicine: Endocrinology and Infertility

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