The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps

Authors

  • Aytekin Tokmak Department of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara
  • Ebru Ersoy Department of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara
  • Ali Özgür Ersoy Department of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara
  • Esra Yaşar Çelik Department of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara
  • Ali İrfan Güzel Department of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara
  • Mustafa Uğur Department of Obstetrics and Gynecology Dr. Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara

Keywords:

Endometrial polyp, Reproductive age, Risk factors

Abstract

OBJECTIVE: To compare clinical and laboratory parameters in middle and advanced reproductive age women with endometrial polyps.
STUDY DESIGN: We designed a retrospective study among reproductive age women who were managed at our clinic with the diagnosis of endometrial polyps. Thirty seven women older than 40 years of age (study group), and 113 women younger than 40 years (control group) were compared in terms of various clinical and laboratory parameters including age, body mass index (BMI), gravidity, parity, abortion, basal hormone levels, tumor markers, complete blood count values, smoking status, presence of polycystic ovary syndrome (PCOS), infertility status, co-morbidities, and number and size of endometrial
polyps.
RESULTS: The mean age of patients in the study and control groups were 45.2±3.5 and 30.6±4.9 years, respectively (p<0.001). The median BMI, gravidity, parity and abortion were significantly higher in study group (p<0.05). Infertility was more common in control group (65.5% vs. 10.8%; p<0.001). Fasting plasma glucose, basal FSH (follicle stimulating hormone) and estradiol (E2) levels were higher in study group than control group (p<0.05). Mean tumor marker levels were similar in both groups. Complete blood count values, smoking status, presence of PCOS, and number and size of polyps did not differ
significantly between the two groups. The most common location of endometrial polyps within the uterine cavity was the posterior wall. There was no correlation between number and size of polyps and basal hormone levels (p>0.05).
CONCLUSION: According to this study, 40 years of age and older women with endometrial polyps were more obese and had higher basal FSH and E2 levels. Obesity and increased estrogen levels may be contributing risk factors for developing endometrial polyps in women over 40 years of age.

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Published

2014-12-30

How to Cite

1.
Tokmak A, Ersoy E, Ersoy A Özgür, Yaşar Çelik E, Güzel A İrfan, Uğur M. The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps. Gynecol Obstet Reprod Med [Internet]. 2014Dec.30 [cited 2021May6];20(3):154-8. Available from: https://www.gorm.com.tr/index.php/GORM/article/view/163

Issue

Section

Reproductive Medicine: Endocrinology and Infertility

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