Is HbA1c Predictive for Screening and Diagnosis of Gestational Diabetes Mellitus?

Authors

  • Neslihan Yerebasmaz Perinatology Department of Etlik Zübeyde Hanım Women’s Health Research and Educational Hospital, Ankara
  • Oya Aldemir Perinatology Department of Etlik Zübeyde Hanım Women’s Health Research and Educational Hospital, Ankara
  • Şeyma Asıltürk Perinatology Department of Etlik Zübeyde Hanım Women’s Health Research and Educational Hospital, Ankara
  • Deniz Esinler Perinatology Department of Etlik Zübeyde Hanım Women’s Health Research and Educational Hospital, Ankara
  • Ertuğrul Karahanoğlu Perinatology Department of Etlik Zübeyde Hanım Women’s Health Research and Educational Hospital, Ankara
  • Ömer Kandemir Perinatology Department of Etlik Zübeyde Hanım Women’s Health Research and Educational Hospital, Ankara
  • Serdar Yalvaç Perinatology Department of Etlik Zübeyde Hanım Women’s Health Research and Educational Hospital, Ankara

Keywords:

Gestational diabetes mellitus, HbA1c, OGTT

Abstract

OBJECTIVE: Evaluation of HbA1c value in diagnosis of gestational diabetes mellitus.
STUDY DESIGN: This retrospective cohort study included 131 women with gestational diabetes mellitus (GDM) that were screened and diagnosed between the 24-28 weeks of gestation by two-step testing regimen in Etlik Zübeyde Hanım Women’s Health Research and Educational Hospital. Venous blood samples of these women were collected for HbA1c. One sample test was performed to test the difference
between our HbA1c results and the value in the literature.
RESULTS: The mean HbA1c result in our study was 5.6% (min:4.4%, max:8.0%), standard deviation was 0.5. We compared our results with the cut off value of 5.5 % that was notified for second trimester for non-diabetic pregnancies by different authors. Our HbA1c value that was 5.6% was significantly higher than the cut off values (5.5%) that was reported (p=0.008).
CONCLUSION: There is an ambiguity for the threshold values of HbA1c in GDM. Further studies are needed to evaluate true cut-off values for using HbA1c for screening and diagnosing GDM.

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Published

2014-08-29

How to Cite

1.
Yerebasmaz N, Aldemir O, Asıltürk Şeyma, Esinler D, Karahanoğlu E, Kandemir Ömer, Yalvaç S. Is HbA1c Predictive for Screening and Diagnosis of Gestational Diabetes Mellitus?. Gynecol Obstet Reprod Med [Internet]. 2014Aug.29 [cited 2022Jan.27];20(2):88-91. Available from: https://www.gorm.com.tr/index.php/GORM/article/view/142

Issue

Section

Obstetrics; Maternal Fetal Medicine and Perinatology

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