Comparison of Cycle Outcomes Among Women with Endometrioma or Non-Functional Cysts Versus Control

Authors

DOI:

https://doi.org/10.21613/GORM.2020.1110

Keywords:

cysts, Endometrioma, In vitro fertilization, The clinical pregnancy rate

Abstract

OBJECTIVE: This study aimed to compare cycle outcomes among women with endometrioma or non-functional cysts versus control.

STUDY DESIGN: Women under 35 years of age with unexplained infertility underwent in vitro fertilization cycle. Two hundred and ninety-nine women were included in this study. Study groups consist of women with endometrioma (n=82) or non-functional ovarian cysts (n=100) and control group (n=117). Women in each group were selected consecutively. Groups were matched for age and ovarian reserve and compared in terms of in vitro fertilization cycle outcome.

RESULTS: There were no significant differences among groups in terms of mean age, early follicular phase Follicle-Stimulating Hormone, and anti-müllerian hormone levels (p>0.05). Baseline total antral follicle counts were similar among groups (p>0.05). There were significant differences among groups in terms of mean starting and total gonadotropin dose, peak estradiol level, total oocyte number, and mature oocyte numbers (p<0.05). Clinical pregnancy rates were 10.7%, 17.3%, and 31.6% in groups with non-functional cyst, endometrioma and control group respectively (p<0.05). The presence of a non-functional cystic mass of ovary on the starting day of stimulation was a risk factor for poor cycle outcome in terms of clinical pregnancy rates [OR=0.5 (95 % CI; 0.2-0.9, p=0.03)].

CONCLUSION: Our data showed that the presence of any kind of cystic mass of the ovary especially the non-functional cysts on the starting day of stimulation was a risk factor for poor cycle outcomes in terms of clinical pregnancy rates.

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Published

2021-01-15

How to Cite

1.
Ozkaya E, Cogendez E, Tozkir E, Unsal S, Yavuz A, Tunali G, Uzun O, Ergen EB, Eser SK. Comparison of Cycle Outcomes Among Women with Endometrioma or Non-Functional Cysts Versus Control. Gynecol Obstet Reprod Med [Internet]. 2021Jan.15 [cited 2021Apr.15];:1-6. Available from: https://www.gorm.com.tr/index.php/GORM/article/view/1110

Issue

Section

Reproductive Medicine: Endocrinology and Infertility

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